Peptide markers for diagnosis of angiogenesis

G - Physics – 01 – N

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G01N 33/574 (2006.01)

Patent

CA 2674736

The 'present invention relates to a method for detecting physiological or pathological blood' vessel formation, preferably glioma activity, comprising determining the expression level of colligin 2 in blood, cerebrospinal fluid or tissue vasculature. The invention further relates to the use of a method for detecting physiological or pathological blood vessel formation wherein said use is for monitoring a disease process; a healing process; or a response to a disease therapy.

La présente invention concerne un procédé de détection de formations physiologiques ou pathologiques dans des vaisseaux sanguins, de préférence d'une activité tumorale, consistant à déterminer le niveau d'expression de la colligine 2 dans le sang, le liquide céphalorachidien ou le système vasculaire des tissus. L'invention concerne également l'utilisation d'un procédé de détection de formations physiologiques ou pathologiques dans des vaisseaux sanguins, afin de surveiller un processus pathogénique; un processus de guérison; ou une réponse à une thérapie.

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