Detection of preterm labour

Details Detection of preterm labour Detection of preterm labour

G - Physics

01

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G01N 33/94 (2006.01) C12Q 1/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2559091

The invention describes a method for diagnosis of preterm labour in a mammal, comprising measuring levels of an endocannabinoid such as anandamide in a subject. Elevated levels are indicate of preterm labour. The measurement is typically performed during late pregnancy, such as the third trimester in humans. In certain embodiments, endocannabinoid levels may be measured indirectly, for example by measurement of fatty acid amide hydrolase (FAAH) levels.

La présente invention concerne une méthode de diagnostic d'un accouchement prématuré chez un mammifère, ladite méthode consistant à mesurer les taux d'un endocannabinoïde tel que l'anandamide chez une personne. Des taux élevés indiquent un accouchement prématuré. La mesure est particulièrement effectuée en cas de grossesse tardive, chez la femme pendant le troisième trimestre. Dans certaines formes de réalisation, les taux d'endocannabinoïdes peuvent être mesurés indirectement, par exemple, par la mesure des taux de l'amide hydrolase de l'acide gras (FAAH).

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