Heterocyclic derivatives which inhibit factor xa

C - Chemistry – Metallurgy – 07 – D

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C07D 213/82 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2295945

The invention relates to heterocyclic derivatives, or pharmaceutically- acceptable salts thereof, which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect, formula (I).

L'invention concerne des dérivés hétérocycliques ou leurs sels acceptables sur le plan pharmaceutique possédant des propriétés antithrombotiques et anticoagulantes et qui sont, de ce fait, utiles dans des méthodes de traitement de l'homme ou de l'animal. Elle concerne également des procédés servant à préparer ces dérivés hétérocycliques, des compositions pharmaceutiques les contenant et leur mise en application afin de préparer des médicaments conçus pour exercer un effet antithrombotique ou anticoagulant, formula (I).

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