Triptolide c-ring derivatives as anticancer agents and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 493/04 (2006.01) A61K 31/343 (2006.01) A61P 35/00 (2006.01) C07D 307/88 (2006.01)

Patent

CA 2750844

Disclosed are compounds based on C- and D-ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

L'invention concerne des dérivés du triptolide et du triptolide hydroxylé à cycles C et D modifiés pouvant être utilisés dans un traitement antiprolifératif, anticancéreux et immunosuppresseur.

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