Pharmaceutical formulations comprising a long-acting...

Details Pharmaceutical formulations comprising a long-acting... Pharmaceutical formulations comprising a long-acting...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 31/4704 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2617286

The invention relates to a liquid, propellant-free pharmaceutical formulation in the form of ready-to-use preparation for administration by nebulisatio.eta. comprising a water soluble salt of the beta2-agonist 8-hydroxy-5- [1-hydroxy-2- [[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2( 1H)- quinolinone as active ingredient. The active ingredient is chemically stable in the formulation, and said formulation is provided of an adequate shelf-life suitable for commercial distribution, storage and use.

La présente invention concerne une formulation pharmaceutique sans propulseur liquide se présentant sous la forme d'une préparation prête à l'emploi destinée à être administrée par nébulisation et comprenant un sel hydrosoluble de l'agoniste bêta2 8-hydroxy-5-[1-hydroxy-2-[[2-(4-méthoxyphényl)-1-méthyléthyl]amino]éthyl]-2(1H)-quinolinone comme ingrédient actif. L'ingrédient actif est chimiquement stable dans la formulation, laquelle formulation bénéficie d'une durée de conservation adéquate convenant à la distribution, au stockage et à l'utilisation commercial.

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