Percutaneous biological fluid sampling and analyte...

G - Physics – 01 – N

Patent

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G01N 27/26 (2006.01) A61B 5/00 (2006.01) A61B 5/15 (2006.01) A61B 19/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2390332

Devices and methods for sampling a biological fluid and measuring a target constituent within the biological fluid are provided. Generally, the subject devices include a sampling means configured to pierce a skin surface to provide access to biological fluid and concentrically-spaced working and reference electrodes positioned within the elongated sampling means that define an electrochemical cell for measuring the concentration of analyte within the biological fluid. The subject devices and methods are particularly suited for use in the sampling and concentration measuring of glucose in interstitial fluids. Also provided are kits that include the subject devices for use in practicing the subject methods.

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