C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2587891
The present invention relates to novel quinoxaline-piperazine compounds, 1- [(6,7-substituted alkoxyquinoxalinyl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives and their pharmaceutically acceptable salts, a process for their preparation thereof, and compositions containing such compounds. Therapeutic methods for the treatment of hyperproliferative disorders, including cancers, by administering quinoxalin-piperazine compounds are also included.
La présente invention concerne de nouveaux composés de la quinoxaline-pipérazine, à savoir des dérivés de la 1-[(alcoxyquinoxalinyle à substitution en 6,7)aminocarbonyl]-4-(hétéro)arylpipérazine ainsi que leurs sels pharmaceutiquement acceptables, un procédé pour les préparer et des compositions les contenant. Sont aussi concernés par l~invention des procédés thérapeutiques de traitement des troubles hyperprolifératifs, notamment les cancers, par administration de composés de la quinoxaline-pipérazine.
Ahn Chang-Ho
Gong Young-Dae
Jeon Moon-Kook
Kim Dong-Su
Kim Gun-Do
Korea Research Institute Of Chemical Technology
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Rexhan Pharmaceuticals Inc.
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