Methods and reagents for modulating apoptosis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2252422

The invention provides a novel apoptosis protein: p28 Bap31. Also provided are p28 Bap31 polypeptide fragments, p28 Bap31 antisense nucleic acid molecules, anti-p28 Bap31 antibodies, and methods for modulating apoptosis and for detecting compounds which modulate apoptosis.

L'invention concerne une nouvelle protéine de l'apoptose, la protéine p28 Bap31, des fragments polypeptidiques de celle-ci, des molécules d'acide nucléique antisens de cette protéine p28 Bap31, ainsi que des anticorps dirigés contre celle-ci. L'invention concerne également des procédés servant à moduler l'apoptose et à détecter des composés modulant celle-ci.

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