Methods and systems for quantifying

G - Physics – 01 – N

Patent

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G01N 33/68 (2006.01)

Patent

CA 2660881

Methods and systems for quantifying at least two isobaric labels and/or peptides labeled with different isobaric labels are disclosed. In certain examples, the method comprises fitting a mathematical function to at least two isobaric label fragment peaks in a mass spectrum to quantify simultaneously an amount of at least one peptide present in two different samples.

La présente invention concerne des procédés et systèmes destinés à quantifier au moins deux traceurs isobares et/ou peptides marqués par des traceurs isobares différents. Dans certains exemples, le procédé comprend l'étape consistant à ajuster une fonction mathématique à au moins deux pics de fragment de traceur isobare dans un spectre de masse de manière à quantifier simultanément une quantité d'au moins un peptide présent dans deux échantillons différents.

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