Morphine and diamorphine salts of anionic non-narcotic...

C - Chemistry – Metallurgy – 07 – D

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C07D 489/04 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2247616

The present invention relates to morphine and diamorphine salts of anionic non- narcotic analgesics belonging to the type of substituted carboxylic acids, preferably the morphine and diamorphine salts of diclofenac (formula 1); to processes for heir production, the use of these salts in the treatment of diseases, as well as to pharmaceutical preparations comprising these salts.

L'invention concerne des sels de morphine et de diamorphine d'analgésiques anioniques non narcotiques du type des acides carboxyliques substitués, de préférence des sels de morphine et de diamorphine de diclofénac (formule 1). L'invention concerne en outre des procédés permettant de préparer lesdits sels, leur utilisation pour traiter des affections, ainsi que des préparations pharmaceutiques les contenant.

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