Phosphate derivatives of diaryl 1,3,4-oxadiazolone

C - Chemistry – Metallurgy – 07 – F

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Details

C07F 9/09 (2006.01) A61K 31/675 (2006.01) C07F 9/12 (2006.01) C07F 9/653 (2006.01)

Patent

CA 2318817

The present invention provides novel phosphate derivatives having general formula (I) wherein A, R1 and R2 are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.

La présente invention concerne de nouveaux dérivés phosphoriques de formule générale (I), dans laquelle A, R?1¿, et R?2¿ sont tels que définis dans l'invention. Cette invention concerne également un sel ou un produit de solvatation non toxiques pharmaceutiquement acceptables de ces composés, pouvant être utiles au traitement des troubles liés à l'ouverture de canaux potassium.

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