Low molecular weight hyaluronic acid for the treatment of...

A - Human Necessities – 61 – K

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Details

A61K 31/728 (2006.01) A61K 31/70 (2006.01) A61K 31/7008 (2006.01) A61K 31/7012 (2006.01) A61K 31/702 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07H 5/06 (2006.01) C07H 7/033 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2519797

The present invention provides a therapeutic agent for nerve damages such as those caused by spinal cord injury or nerve trauma, which comprises, as an active ingredient, a low-molecular-weight saccharide composed of at least glucuronic acid and/or N-acetylglucosamine or a pharmaceutically acceptable salt thereof. The present invention also provides a therapeutic agent for nerve damages which comprises, as an active ingredient, preferably a low-molecular-weight hyaluronic acid, more preferably hyaluronic acid disaccharide to hyaluronic acid 2,500-saccharide, further more preferably hyaluronic acid disaccharide to hyaluronic acid 50-saccharide, much more preferably hyaluronic acid tetrasaccharide, or a pharmaceutically acceptable salt thereof.

L'invention concerne un remède contre une lésion nerveuse provoquée par une lésion cérébrale, un traumatisme nerveux ou un événement similaire. Ce remède contient, en tant qu'ingrédient actif, un saccharide de poids moléculaire bas dont le ou les sucres constituant consistent en acide glucuronique et/ou N-acétylglucosamine, ou un de ses sels acceptable sur le plan pharmaceutique. Remède contre une lésion nerveuse contenant, de préférence, en tant qu'ingrédient actif, acide hyaluronique de poids moléculaire bas, de préférence disaccharide d'acide hyaluronique à 2 500-saccharide d'acide hyaluronique, encore de préférence, disaccharide d'acide hyaluronique à 50-saccharide d'acide hyaluronique, dans un mode de réalisation préféré, tétrasaccharide d'acide hyaluronique, ou un de ses sels acceptable sur le plan pharmaceutique.

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