Treatment of mammalian reaction to ige interactions

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 39/02 (2006.01) A61K 39/395 (2006.01) C07K 1/00 (2006.01) C12N 15/74 (2006.01) A61K 38/11 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2507115

A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a neurotoxin (CnT) derived from Clostridia sp.

L'invention concerne un procédé permettant de bloquer ou de réduire une réaction physiologique chez un mammifère face à l'interaction d'anticorps IgE présents chez ledit mammifère après leur contact avec l'antigène correspondant, au moyen d'administration au mammifère d'une quantité thérapeutiquement efficace de neurotoxine (CnT) dérivée de Clostridia sp.

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