Analysis of predisposition based on human airway tripsin...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12N 9/76 (2006.01) C12N 15/11 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 2315218

A method for predicting the constitution susceptible to the onset of specific diseases in individual humans, for example, respiratory diseases such as chronic obstructive pulmonary diseases, sinobronchial syndrome, pulmonary emphysema, diffuse panbronchiolitis or bronchiectasis, effects of treatment on patients or prognosis of the treatment by analyzing the genetic polymorphisms of a human trypsin-like enzyme of the respiratory tract.

La présente invention concerne un procédé permettant de détecter les prédispositions des individus face à des pathologies spécifiques, par exemple les maladies respiratoires telles que les maladies respiratoires obstructives chroniques, le syndrome sino-bronchique, l'emphysème pulmonaire, la bronchiolite diffuse et la bronchectasie, les effets thérapeutiques sur les patients ou les pronostics établis après traitements, et ceci sur la base du polymorphisme du gène de la tripsine protéase des voies respiratoires humaines.

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