Use of tam receptor inhibitors as antimicrobials

A - Human Necessities – 61 – K

Patent

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A61K 31/519 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2703621

This disclosure concerns antimicrobial compositions and methods for immunoenhancement, for example methods of increasing production of a type I interferon (IFN) in response to pathogen infection, by administration of a TAM receptor inhibitor. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor to treat a viral or bacterial infection in a subject.

L'invention porte sur des compositions antimicrobiennes et sur des procédés pour une immuno-amélioration, par exemple sur des procédés consistant à augmenter la production d'un interféron de type I (IFN) en réponse à une infection par un pathogène, par l'administration d'un inhibiteur de récepteurs TAM. Dans certains modes de réalisation, l'invention porte sur des procédés d'utilisation d'un inhibiteur de récepteurs TAM pour traiter une infection virale ou bactérienne chez un sujet.

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