Process for the preparation of 8a-aza-8a-homoerythromycin...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/00 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2068951

18325 TITLE OF THE INVENTION NOVEL PROCESS FOR THE PREPARATION OF 8a-aza-8a-HOMOERYTHROMYCIN CYCLIC LACTAMS ABSTRACT OF THE INVENTION A method of synthesizing cyclic lactams of the general structural formula Image wherein R is hydrogen or C1-10 alkyl. These compounds are macrolides useful as antibiotics and as intermediates for the synthesis of other macrolide antibiotics.

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