Rb pathway and chromatin remodeling genes that antagonize...

Details Rb pathway and chromatin remodeling genes that antagonize... Rb pathway and chromatin remodeling genes that antagonize...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/00 (2006.01) C07K 16/18 (2006.01) C12N 1/00 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2498928

In general, the invention provides methods and compositions useful in the treatment of a neoplasia. These compositions include new components of the Rb pathway that function in chromatin remodeling and antagonize Ras signaling.

L'invention concerne généralement des méthodes et des compositions utiles dans le traitement d'une néoplasie. Ces compositions comprennent de nouveaux éléments de la voie du Rb qui interviennent dans le remodelage de la chromatine et sont des antagonistes de la signalisation de Ras.

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