C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) C07K 14/47 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2340938
Antibodies which specifically bind to nuclear matrix proteins (NMP) BLCA-1 to BLCA-6 which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP.
L'invention concerne des protéines à matrice nucléaire caractérisées par une expression définie dans le tissu, qui sont des marqueurs utiles pour le diagnostic et le phasage de la malignité d'une cellule, et pour le traitement des troubles de prolifération cellulaire associés auxdites protéines. L'invention concerne également des polypeptides sensiblement purifiés et des séquences nucléotidiques codant les protéines en question.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Pittsburgh
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