Plasmodium falciparum blood-stage antigen, the preparation...

Details Plasmodium falciparum blood-stage antigen, the preparation... Plasmodium falciparum blood-stage antigen, the preparation...

C - Chemistry, Metallurgy

12

N

C12N 15/30 (2006.01) A61K 39/015 (2006.01) C07K 14/445 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2061575

BEHRINGWERKE AKTIENGESELLSCHAFT 91/B 002 - Ma 862 Dr. Lp/Bi ABSTRACT OF THE DISCLOSURE A Plasmodium falciparum blood-stage antigen, the prepara- tion and use thereof The invention relates to a DNA sequence which is highly homologous with that of a glycophorin-binding protein, which is called GBP 130, and has therefore been desig- nated GBP 130 h. The invention additionally relates to the protein GBP 130 h from Plasmodium falciparum itself and to a process for the preparation thereof by recom- binant DNA techniques. Finally, the invention relates to the use of the protein GBP 130 h from Plasmodium fal- ciparum for the preparation of malaria vaccines.

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