Treating inflammatory conditions

Details Treating inflammatory conditions Treating inflammatory conditions

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) A61M 1/36 (2006.01) B01J 20/32 (2006.01)

Patent

CA 2736632

An apheresis column loaded with a solid support comprises one or more chemokines, in particular biotinylated chemokines, immobilized directly or indirectly on the support, in particular on a support carrying streptavidin. Also disclosed are uses of the column and the support and a method of depleting cells, in particular leukocytes, from the peripheral blood of a person suffering from an inflammatory condition such as Inflammatory Bowel Disease (IBD).

Linvention concerne une colonne daphérèse chargée dun support solide comprenant une ou plusieurs chimiokines, en particulier des chimiokines biotinylées immobilisées directement ou indirectement sur le support, notamment sur un support portant une streptavidine. Linvention concerne également les utilisations de la colonne et du support et une méthode de déplétion de cellules, en particulier des leucocytes provenant du sang périphérique dune personne souffrant dun état inflammatoire, tel quune maladie intestinale inflammatoire (IBD)

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