Naphthyl glyoxamides as spla2 inhibitors

Details Naphthyl glyoxamides as spla2 inhibitors Naphthyl glyoxamides as spla2 inhibitors

C - Chemistry, Metallurgy

07

C

C07C 235/78 (2006.01) A61K 31/185 (2006.01) A61K 31/195 (2006.01) A61K 31/66 (2006.01) C07C 309/11 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2240404

A class of novel naphthyl glyoxamide compounds is disclosed together with a process for making the novel naphthyl glyoxamide compounds and the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

L'invention concerne une catégorie de nouveaux composés de naphtylglyoxamides ainsi qu'un procédé relatif à la fabrication de ces composés et à leur utilisation pour inhiber la libération d'acides gras, induite par sPLA¿2?, pour le traitement d'affections telle que le choc septique.

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