Hfa-suspension formulations of crystalline tiotropium...

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A61K 9/12 (2006.01) A61K 31/46 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2479638

The invention relates to propellant formulations containing suspensions of a crystalline anhydrate of (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-7- [(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9- azoniatricyclo[3.3.1.02,4]nonane bromide.

L'invention concerne des suspensions d'un anhydrate cristallin de bromure de (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-7-[(hydroxydi-2-thiénylacétyl)oxy]-9,9-diméthyl-3-oxa-9-azoniatricyclo[3.3.1.0?2,4¿]nonane, qui contiennent des formulations de gaz propulseur.

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