Processes and intermediates for preparing...

Details Processes and intermediates for preparing... Processes and intermediates for preparing...

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) C07C 229/34 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2311872

The present invention provides novel processes for preparing 3(S)-[(5-chloro- 1H-indole-2-carbonyl)-amino)-2(R)-hydroxy-4-phenyl-butyric acid. Also provided are novel intermediates used in those processes. Further, the 3(S)-[(5-chloro-1H- indole-2- carbonyl)-amino]-2(R)-hydroxy-4-phenyl-butyric acid prepared by the novel processes can be further reacted to yield known indole 2-carboxamides and derivatives thereof possessing glycogen phosphorylase inhibitory activity, which are useful in the treatment of mammals, especially human beings, having glycogen phosphorylase dependent diseases or conditions.

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