A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61J 3/06 (2006.01) A61K 9/28 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2669324
Disclosed is a method for producing a sustained release tablet comprising a pharmaceutical component which can be administered through an oral route, in a simple manner while maintaining the uniform content of the pharmaceutical component in the tablet. An excipient and an enteric coating agent are granulated while spraying a solution or suspension of a pharmaceutical component which can be administered through an oral route, thereby producing a granule A. The granule A is mixed with a mixture B which contains a hydrogel-forming substance, and the resulting mixture is shaped into a tablet.
La présente invention concerne un procédé de production d'un comprimé à libération prolongée, comprenant un composant pharmaceutique qui peut être administré par voie orale, d'une manière simple, tout en permettant la conservation du contenu uniforme du composant pharmaceutique dans le comprimé. Un excipient et un agent d'enrobage gastrorésistant sont granulés pendant que l'on vaporise une solution ou une suspension d'un composant pharmaceutique qui peut être administré par voie orale, produisant ainsi un granule A. Le granule A est mélangé à un mélange B qui contient une substance formant un hydrogel, et le mélange en résultant est modelé sous la forme d'un comprimé.
Kazama Kazuo
Nakashima Katashi
Kyorin Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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