Process for the production of tibolone

Details Process for the production of tibolone Process for the production of tibolone

C - Chemistry, Metallurgy

07

J

C07J 1/00 (2006.01) C07J 75/00 (2006.01) C07J 5/00 (2006.01)

Patent

CA 2517934

Disclosed is a process for the synthesis of 17.beta.-hydroxy-7.alpha.-methyl- 19-nor-17.alpha.-pregn-5(10)-ene-20-yne-3-one (tibolone, 11) and intermediates useful for the synthesis thereof: (11).

L'invention concerne un procédé permettant la synthèse de 17?-hydroxy-7?-méthyl- 19-nor-17?-pregn-5(10)-ène-20-yne-3-one (tibolone, 11), ainsi que des intermédiaires utiles pour cette synthèse : (11).

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