Coated microstructures and method of manufacture thereof

A - Human Necessities – 61 – F

Patent

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A61F 2/06 (2006.01)

Patent

CA 2612005

Coated microneedle devices and methods of making such devices are provided. In one aspect, a method for coating includes providing a microstructure having at least one surface in need of coating; and applying a coating liquid, which comprises at least one drug, to the at least one surface of the microstructure, wherein the surface energy of the coating liquid is less than the surface energy of the surface of the microstructure. The coating liquid may include a viscosity enhancer and surfactant. Microneedles having heterogeneous coatings, pockets, or both are also provided.

La présente invention concerne des dispositifs de micro-aiguille revêtues et des procédés de fabrication de ces dispositif. Dans un aspect, cette invention concerne un procédé de revêtement qui consiste à prendre une microstructure possédant au moins une surface nécessitant un revêtement, à appliquer un liquide de revêtement qui comprend au moins un médicament sur la surface de cette microstructure, l'énergie de surface de ce liquide de revêtement étant inférieure à l'énergie de surface de la surface de la microstructure. Ce liquide de revêtement peut comprendre un renforçeur de viscosité et un tensioactif. Cette invention concerne aussi des micro-aiguilles possédant des revêtements hétérogènes, des poches ou les deux.

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