Bioactive prostheses with immunosuppressive, antistenotic...

A - Human Necessities – 61 – L

Patent

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A61L 31/10 (2006.01) A61L 27/28 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 31/16 (2006.01) A61L 33/00 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2349930

The invention concerns a bioactive prosthesis comprising a support coated with a polymer layer with reactive functions, and a bioactive substance fixed on the prosthesis via said reactive functions so as to be gradually released on a site for implanting the prosthesis. Such prostheses are useful in the field of cardiology to avoid for example restenosis resulting from implantation of stents in coronary arteries.

L'invention concerne une prothèse bioactive comprenant un support revêtu d'une couche de polymère à fonctions réactives, et une substance bioactive fixée sur la prothèse par l'intermédiaire desdites fonctions réactives de façon à pouvoir être libérée progressivement sur un site d'implantation de la prothèse. De telles prothèses sont utiles dans le domaine de la cardiologie pour éviter par exemple les resténoses résultant de l'implantation d'éndocalibreurs ou "stents" dans les artères coronaires.

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