Casein derived peptides and uses thereof in therapy

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 35/14 (2006.01) A61K 35/20 (2006.01) A61K 38/01 (2006.01) A61K 38/03 (2006.01) A61K 38/17 (2006.01) C07K 5/00 (2006.01) C07K 7/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2458924

Biologically active peptides that are derived from or are similar to sequences identical with the N-terminus of the S1 fraction of milk casein. These peptides are capable of stimulating and enhancing immune response, protecting against viral infection, normalizing serum cholesterol levels, and stimulating hematopoiesis. The casein-derived peptides are non-toxic and can be used to treat and prevent immune pathologies, hypercholesterolemia, hematological disorders and viral-related diseases.

L'invention concerne des peptides actifs biologiquement dérivés de séquences identiques au N-terminus de la fraction .alpha.S1 de la caséine du lait, ou similaires à ces séquences. Ces peptides sont en mesure de stimuler et de renforcer la réaction immunitaire, de protéger contre des infections virales, de normaliser les taux de cholestérol sérique, et de stimuler l'hématopoïèse. Les peptides dérivés de la caséine ne sont pas toxiques et peuvent être utilisés dans le traitement et dans la prévention de pathologies immunitaires, de l'hypercholestérolémie, de troubles hématologiques et de maladies virales.

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