Antisense modulation of pten expression

Details Antisense modulation of pten expression Antisense modulation of pten expression

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2379659

Antisense compounds, compositions and methods are provided for modulating the expression of PTEN. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTEN. Methods of using these compounds for modulation of PTEN expression and for treatment of diseases associated with expression of PTEN are provided.

Composés antisens, compositions et procédés servant à moduler l'expression de PTEN. Ces compositions contiennent des composés antisens, en particulier des oligonucléotides antisens, ciblés à des acides nucléiques codant PTEN. Procédés d'utilisation de ces composés afin de moduler l'expression de PTEN et de traiter des maladies associées à cette expression.

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