Diabetogenic epitopes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A23L 1/29 (2006.01) A61P 3/10 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 17/00 (2006.01) C12N 15/82 (2006.01) G01N 33/02 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2452162

The present invention provides nucleotide and amino acid sequences of diabetogenic epitopes, and proteins comprising diabetogenic epitopes. Also provided are kits comprising diabetogenic epitopes, methods of identifying subjects comprising antibodies to diabetogenic epitopes and foodstuffs modified to remove or reduce diabetogenic epitopes or proteins comprising diabetogenic epitopes. Diabetogenic epitopes and proteins comprising diabetogenic epitopes from .alpha./.beta.- gliadin A-II precursor, .alpha./.beta.-gliadin MM1 precursor, or Glb1 are also disclosed.

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