C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/15 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2751987
Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use there-of, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed that have lower neurotoxicity effects than other compounds.
L'invention concerne des compositions et des procédés dans des modes de réalisation relatifs à l'induction de la mort cellulaire notamment dans des cellules cancéreuses. L'invention concerne des composés et les procédés associés pour leur synthèse et leur utilisation, y compris l'utilisation des composés dans une thérapie pour le traitement du cancer et l'induction sélective de l'apoptose dans des cellules. Les composés de l'invention possèdent des effets neurotoxiques plus légers que les autres composés.
Fan Timothy M.
Hergenrother Paul Joseph
Hsu Danny Chung
Novotny Chris J.
Peterson Quinn Patrick
Mckay-Carey & Company
The Board Of Trustees Of The University Of Illinois
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