In vitro model of focal ischemia

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2741460

A method of modeling in vitro focal ischemia comprising: perfusing a tissue slice in vitro with an oxygenated medium; and, applying a focal insult to a targeted portion of the tissue slice. The method is particularly useful for brain tissue.

La présente invention concerne un procédé de modélisation in vitro dune ischémie focale comprenant : la perfusion in vitro dune coupe de tissu avec un milieu oxygéné; et lapplication dune attaque focale sur une partie ciblée de la coupe de tissu. Le procédé est particulièrement utile pour le tissu cérébral.

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