Polymorphisms associated with cardiac arrythmia

Details Polymorphisms associated with cardiac arrythmia Polymorphisms associated with cardiac arrythmia

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2421747

The invention relates generally to the discovery of specific nucleotide polymorphisms in the KCNE2 gene and the association of these polymorphisms with antibiotic-induced LQTS. Related composition screening systems and diagnostic and prognostic assays are provided.

De façon générale, cette invention concerne la découverte de polymorphismes nucléotidiques spécifiques dans le gène KCNE2 et l'association de ces polymorphismes avec le syndrome du QT long induit par des antibiotiques. Sont également décrits des systèmes connexes de criblage de compostions ainsi que des essais diagnostics et pronostiques.

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