Thienopyridazines as ikk inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/381 (2006.01)

Patent

CA 2563990

The invention is concerned with a compound of formula (I): or a pharmaceutically acceptable salt, a solvate or a prodrug thereof, wherein A, Y, Z and Rl are as defined in the description and the claims. These compounds inhibit IKK and can be used as medicaments.

L'invention concerne un composé représenté par la formule (I), ou un sel acceptable d'un point de vue pharmaceutique, un solvate ou un promédicament de celui-ci. A, Y, Z et R?1¿ sont tels que définis dans la description et les revendications. Ces composés inhibent les kinases IKK et peuvent être utilisés comme médicaments.

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