Osteogenic composition including a complex growth...

A - Human Necessities – 61 – K

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A61K 47/02 (2006.01) A61K 9/10 (2006.01) A61K 38/18 (2006.01) A61L 27/44 (2006.01) A61L 27/52 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2720203

The invention relates to an open implant comprising an osteogenic composition including at least: a complex osteogenic/polysaccharide amphiphilic anionic growth factor, a soluble cation salt that is at least divalent, and an organic substrate said organic substrate does not including any demineralized bone matrix. In one embodiment, said implant is in freeze-dried form. The invention also relates to the preparation method thereof.

L'invention concerne un implant ouvert constitué d'une composition ostéogénique comprenant au moins : .cndot. un complexe facteur de croissance ostéogénique/polysaccharide anionique amphiphile, .cndot. un sel soluble de cation au moins divalent, et .cndot. un support organique .cndot. ledit support organique ne comprenant pas de matrice d'os déminéralisé. Dans un mode de réalisation ledit implant est sous forme de lyophilisât. Elle concerne également son procédé de préparation.

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