.beta.-hydroxyethylamines having a 1,1-disubstituted...

Details .beta.-hydroxyethylamines having a 1,1-disubstituted... .beta.-hydroxyethylamines having a 1,1-disubstituted...

C - Chemistry, Metallurgy

07

C

C07C 323/30 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 217/52 (2006.01) C07C 217/74 (2006.01) C07D 209/14 (2006.01) C07D 211/58 (2006.01) C07D 213/38 (2006.01) C07D 213/53 (2006.01) C07D 261/08 (2006.01) C07D 277/04 (2006.01) C07D 295/084 (2006.01) C07D 295/092 (2006.01) C07D 317/58 (2006.01) C07D 333/28 (2006.01)

Patent

CA 2056311

- 1 - HOE 90/F 356 Abstract .beta.-Hydroxyethylamines having a 1,1-disubstituted cyclo- propyl radical, a process for their preparation and their use Compounds I Image I where R(1) is t-butyl or an aromatic compound, R(2) is OH, Hal, alkyl(phenyl)carbonyloxy, alkyloxy or benzyloxy, R(3) is (cyclo)alk(en)(yn)yl or an aromatic compound, R(4) is H, alk(en)yl or benzyl, R(5) is H, (cyclo)alk(en)yl or phenylalk(en)yl or R(4) and R(5) are a (CH2)4-6 chain, and X is O, S, SO2 or SO, have antimycotic activity, and are also used for prophy- laxis and exhibit inhibition of the phospholipase of Candida albicans.

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