C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/88 (2006.01) A61K 31/445 (2006.01) C07C 255/41 (2006.01) C07D 211/22 (2006.01) C07D 213/57 (2006.01) C07D 333/24 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2244771
The invention relates to glutarimides of formula (I): (See formula I) in which Ar represents a phenyl non substituted or substituted one or more times with one of the substituents selected from a halogen atom, a hydroxyl, a (C1- C4)alkoxy, a trifluoromethyl, a (C1-C4)alkyl, said substituents being identical or different ; a pyridyl group ; a thienyl group and X is methylene or ethylene, their salts and their enantiomers, as well as their method of preparation and their use for the preparation of the corresponding 3,3-disubstituted piperidines.
L'invention concerne des glutarimides de formule (I), dans laquelle Ar représente un phényle non substitué ou substitué une ou plusieurs fois par un des substituants choisis parmi un atome d'halogène, un hydroxyle, un (C1-C4)alcoxy, un trifluorométhyle, un (C1-C4)alkyle, lesdits substituants étant identiques ou différents; un groupe pyridyle; un groupe thiényle et X est méthylène ou éthylène, leurs sels et leurs énantiomères, ainsi que leur procédé de préparation et leur utilisation pour la préparation des pipéridines 3,3-disubstituées correspondantes.
Camus Philippe
Descamps Marcel
Radisson Joel
Sanofi
Sanofi-Aventis
Sim & Mcburney
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