Use of corrinoids for application in skin diseases

A - Human Necessities – 61 – K

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A61K 31/714 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2451579

The invention relates to the use of the compounds of formula (I), wherein R represents CN, OH, CH3 or H2O, for building up and improving the resistance of the skin. The compounds are particularly suitable for prophylaxis in cases where a predisposition for chronic skin diseases exists, for the prophylaxis and treatment of allergic skin reactions, for the treatment of acute skin lesions, for example burns and wounds, as well as for skin aging and for the treatment of degenerate cells, such as in canceroses, benign and/or malign tumors.

L'invention concerne l'utilisation de composés de formule (I) dans laquelle R représente CN, OH, CH¿3? ou H¿2?O, pour constituer et améliorer la résistance cutanée. Ces composés sont conçus en particulier pour prévenir des maladies cutanées chroniques en cas de prédisposition, prévenir et traiter des réactions cutanées allergiques, traiter des lésions cutanées aiguës telles que des brûlures et des plaies ainsi que le vieillissement cutané, et pour traiter des cellules dégénérées, par exemple en cas de cancer, de tumeurs bénignes et/ou malignes.

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