Methods of using and compositions comprising...

Details Methods of using and compositions comprising... Methods of using and compositions comprising...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) C07D 401/04 (2006.01) C07K 14/435 (2006.01) C07K 14/52 (2006.01) C07K 14/53 (2006.01) C07K 14/54 (2006.01) C07K 14/55 (2006.01)

Patent

CA 2562715

Methods of treating, preventing and/or managing myelodysplastic syndromes are disclosed. Specific methods encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active ingredient, and/or the transplantation of blood or cells. Specific second active ingredients are capable of affecting or blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

L'invention concerne des procédés de traitement, de prévention et/ou de prise en charge de syndromes myélodysplasiques. Des procédés déterminés comprennent l'administration d'un composé immunomodulateur ou de son sel pharmaceutiquement acceptable, de son solvate, de son hydrate, de son stéréoisomère, de son clathrate, ou de leurs promédicaments, isolément ou en combinaison avec un deuxième ingrédient actif, et/ou la transplantation de sang ou de cellules. Les deuxième ingrédients actifs déterminés sont capables d'affecter la production de sang ou de cellules. L'invention concerne également des compositions pharmaceutiques, des formes posologiques à unité isolée et des kits conçus pour s'utiliser avec les procédés de l'invention.

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