C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 305/14 (2006.01)
Patent
CA 2522482
The invention relates to a method for production of 4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,13.alpha.-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene from 4-acetoxy-2.alpha.-benzoyloxy-5.beta.,20- epoxy-1,13.alpha.-dihydroxy-9-oxo-7.beta.-trifluoromethylsulfonyloxy-tax-11-ene by reaction with a molecular sieve in sulpholane.
Procédé de préparation du 4,10.beta.-diacétoxy-2.alpha.-benzoyloxy-5.beta., 20-époxy-1,13.alpha.- dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ène à partir du 4-acétoxy-2.alpha.-benzoyloxy-5.beta., 20- époxy-1,13.alpha.-dihydroxy-9-oxo-7.beta.-trifluorométhylsulfonyloxy-tax- 11-ène par réaction avec un tamis moléculaire dans le sulfolane.
Amouret Guy
Didier Eric
Aventis Pharma S.a.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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