C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/30 (2006.01) A61K 31/4375 (2006.01) A61P 3/04 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2558755
The invention relates to alkyne compounds of general formula (I), wherein the groups and radicals A, B, W, X, Y, Z, R1, and R2 have the meanings indicated in claim 1. The invention further relates to medicaments containing at least one inventive alkyne. The disclosed medicaments are suitable for the treatment of metabolic disorders and/or eating disorders, particularly adiposity and diabetes, as a result of the MCH receptor antagonistic activity thereof.
L'invention concerne des composés alcyne de formule générale (I), dans laquelle les groupes et les restes A, B, W, X, Y, Z, R1 et R2 ont les significations données dans la revendication 1. L'invention concerne en outre des médicaments renfermant au moins un alcyne conforme à l'invention. Du fait de l'activité antagoniste du récepteur de MCH, les médicaments selon l'invention conviennent pour le traitement de troubles métaboliques et/ou de troubles de l'alimentation, en particulier pour le traitement de l'adiposité et du diabète.
Lehmann-Lintz Thorsten
Lotz Ralf R. H.
Lustenberger Philipp
Mueller Stephan Georg
Roth Gerald Juergen
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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