Method and composition for treating cancer by administration...

A - Human Necessities – 61 – K

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A61K 9/52 (2006.01) A61K 9/16 (2006.01) A61K 9/66 (2006.01) A61K 31/337 (2006.01) A61K 38/38 (2006.01) A61K 38/39 (2006.01) A61K 45/06 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2406484

The present invention provides an anti-tumor chemotherapeutic to a patient having a tumor, the composition comprising: microspheres incorporating the anti-tumor chemotherapeutic; and, a suspending solution which surrounds the microspheres. The present invention also provides a method for administering an anti-tumor chemotherapeutic to a patient having a tumor, comprising the steps of delivering the anti-tumor chemotherapeutic as a chemotherapeutic reservoir to the tumor; and, releasing the anti-tumor chemotherapeutic from the chemotherapeutic reservoir to an interstitial space of the tumor in a therapeutically effective amount, wherein, the chemotherapeutic reservoir includes microspheres incorporating the anti-tumor chemotherapeutic and a suspending solution which surrounds the microspheres.

Cette invention concerne l'administration d'une composition chimiothérapeutique anti-cancéreuse à un patient atteint d'une tumeur. La composition comprend des microsphères contenant la substance chimiothérapeutique anti-cancéreuse, et une solution de suspension entourant les microsphères. L'invention concerne également une méthode servant à administrer une substance chimiothérapeutique anti-cancéreuse à un patient atteint d'une tumeur. La méthode consiste à acheminer la substance chimiothérapeutique anti-cancéreuse contenue dans un réservoir chimiothérapeutique vers la tumeur; elle consiste ensuite à libérer la substance chimiothérapeutique anti-cancéreuse du réservoir, en quantités thérapeutiques effectives, afin de l'administrer dans un espace interstitiel de la tumeur. Le réservoir chimiothérapeutique comprend des microsphères contenant la substance chimiothérapeutique anti-cancéreuse, et une solution de suspension entourant les microsphères.

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