Methods for the diagnosis, prognosis and treatment of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2278782

The nucleic acid upstream of the TIGR protein encoding sequence can be used to diagnose glaucoma. Polymorphisms, base substitutions, base additions located with the upstream and within TIGR exons can also be used to diagnose glaucoma. In addition, polymorphisms, base substitutions, base additions located with the upstream and within TIGR exons can also be used to prognose glaucoma.

On peut utiliser l'acide nucléique situé en amont de la séquence codant la protéine TIGR afin de diagnostiquer le glaucome. On peut également utiliser des polymorphismes, des substitutions de bases, des additions de bases situées au moyen des exons amont et à l'intérieur des exons TIGR afin de diagnostiquer le glaucome. De plus, on peut également utiliser des polymorphismes, des substitutions de bases, des additions de bases situées au moyen des exons amont et à l'intérieur des exons TIGR afin de pronostiquer le glaucome.

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