Botulinum toxin pharmaceutical compositions

A - Human Necessities – 61 – K

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A61K 38/16 (2006.01) A61K 38/48 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61K 9/19 (2006.01)

Patent

CA 2400318

A botulinum toxin pharmaceutical composition free of blood derived albumin, comprising a botulinum toxin, sodium chloride or water and a polysaccharide such as a hydroxyethyl starch and/or an amino acid, the pharmaceutical composition being suitable for therapeutic administration to a human patient. Alternately, the polysaccharide and amino acid can be replaced by recombinant albumin.

L'invention concerne une composition pharmaceutique à base de toxine botulique et exempte d'albumine dérivée du sang, comprenant une toxine de botulinum, du chlorure de sodium ou de l'eau et un polysaccharide tel que l'amidon hydroxyéthylé et/ou un acide aminé. Cette composition pharmaceutique convient à l'administration thérapeutique à un patient. Le polysaccharide et l'acide aminé peuvent éventuellement être remplacés par de l'albumine recombinante.

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