C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) A61K 31/07 (2006.01) A61K 38/44 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12Q 1/26 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2448933
The present invention provides a novel retinoic acid metabolizing cytochrome P450, P450RAI-3, that is predominantly expressed in the adrenal gland. Methods for and uses of the new polynucleotide, polypeptide, fragments thereof and modulators thereof, include the treatment of cancer.
La présente invention concerne un nouveau cytochrome P450 métabolisant l'acide rétinoïque, le P450RAI-3, principalement exprimé dans la glande surrénale. Elle concerne également des méthodes et des utilisations du nouveau polynucléotide, polypeptide, et leurs fragments et modulateurs, notamment pour le traitement du cancer.
Petkovich P. Martin
Ramshaw Heather
Wisniewski Jan
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cytochroma Inc.
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