A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 45/00 (2006.01) A61P 3/00 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01) C12N 15/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) C12N 9/12 (2006.01)
Patent
CA 2654735
Disclosed are compositions and methods related to PAS Kinase (PASK) and various diseases and disorders associated therewith. Included are methods for treating insulin resistance, cancer, and diabetes comprising administering a composition that inhibits PAS Kinase. Further included are methods, including high throughput screening methods, for identifying test compounds that modulate PAS Kinase.
La présente invention concerne des compositions et des procédés relatifs à la PAS Kinase ainsi que des maladies et troubles variés y étant associés. L'invention concerne également des méthodes pour traiter la résistance à l'insuline, le cancer et le diabète, qui intégrent l'administration d'une composition inhibant la PAS kinase. L'invention concerne en outre des procédés comprenant également des procédés de criblage à haut rendement, pour identifier des composés de référence qui modulent la PAS kinase.
Hao Huai-Xiang
Rutter Jared
Swiatek Wojtek
Gowling Lafleur Henderson Llp
University Of Utah Research Foundation
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