Dual inhibitors of cholesterol ester and wax ester synthesis...

A - Human Necessities – 61 – K

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Details

A61K 31/255 (2006.01) A61P 17/00 (2006.01) A61P 17/08 (2006.01) A61P 17/10 (2006.01)

Patent

CA 2398219

The present invention provides a method of treating sebaceous gland disorders comprising administering to a patient in need of said treatment an effective amount of a compound named [(2,4,6-triisopropyl-phenyl)-acetyl]-sulfamic acid 2,6-diisopropyl-phenyl ester or a pharmaceutically acceptable salt thereof. Particularly, methods of treating sebaceous gland disorders are provided wherein said disorders are selected from seborrhea, acnes, perioral dermatitis, rosacea, and corticosteroid-induced acneiform lesions. The present invention provides methods of treating acnes such as, for example, chloracne, ciliaris acne, cystic acne, keratosa acne, vulgaris acne, senile acne, and medicinal acne.

La présente invention porte sur un procédé de traitement des troubles des glandes sébacées, ce procédé consistant à administrer à un patient une quantité effective d'un composé appelé [(2,4,6-triisopropyl-phényl)-acétyl]-acide sulfamique 2,6-diisopropyl-phényl ester ou d'un sel de celui-ci acceptable d'un point de vue pharmaceutique. L'invention porte notamment sur des procédés de traitement des troubles des glandes sébacées tels que séborrhée, acné, dermite périorale, acné rosacée et lésions acnéiformes induites par des corticostéroïdes. La présente invention porte sur des procédés de traitement des acnés telles que la chloracné, l'acné ciliaire, l'acné cystique, l'acné kératosique, l'acné vulgaire, l'acné sénile, et l'acné induite par les médicaments.

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