Interleukin-1 homolog zil1a4

Details Interleukin-1 homolog zil1a4 Interleukin-1 homolog zil1a4

C - Chemistry, Metallurgy

12

N

C12N 15/25 (2006.01) A61K 38/20 (2006.01) A61P 37/02 (2006.01) C07K 14/545 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2348431

Homologs of interleukin-1, materials and methods for making them, compositions comprising them, and methods of using them are disclosed. The invention includes polypeptides comprising residues 60 through 218 of SEQ ID NO:7 or residues 1 through 157 of SEQ ID NO:10. Polypeptides and polynucleotides of the invention are useful within diagnostic, therapeutic, and analytical fields, including modulation of immune responses.

L'invention concerne des homologues d'interleukine-1, des matériaux, des techniques de production desdits homologues, des compositions comprenant ces homologues, et leurs méthodes d'utilisation. L'invention concerne également des polypeptides comprenant des résidus 60 à 218 de SEQ ID NO:7 ou des résidus 1 à 157 de SEQ ID NO:10. Les polypeptides et les polynucléotides de l'invention sont utiles dans les domaines diagnostique, thérapeutique, et analytique, notamment la modulation de réponses immunitaires.

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