Use of a nuclease inhibitor or interleukin-10 (il-10) for...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) C07K 14/54 (2006.01) C12N 15/87 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2295510

Described is the use of a nuclease inhibitor or of interleukin-10 (IL-10) for the preparation of a therapeutic composition for improving transfection of a polynucleotide into a cell, and to compositions comprising a mixture of polynucleotide and nuclease inhibitor and/or interleukin-10.

Cette invention, qui a trait à l'utilisation d'un inhibiteur de nucléase ou de l'interleukine 10 (IL-10) dans la préparation d'une composition thérapeutique visant à améliorer la transfection d'un polynucléotide dans une cellule, concerne également des compositions renfermant un mélange d'un polynucléotide et d'un inhibiteur de nucléase et/ou de l'interleukine 10.

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