Process for the preparation of acid chloride compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/78 (2006.01) B01J 27/08 (2006.01) B01J 27/10 (2006.01) C07C 51/00 (2006.01) C07C 51/58 (2006.01) C07C 51/62 (2006.01) C07C 241/00 (2006.01) C07C 243/26 (2006.01) C07D 213/127 (2006.01) C07D 213/26 (2006.01) C07D 213/61 (2006.01) C07D 213/79 (2006.01) C07D 213/81 (2006.01) C07D 237/24 (2006.01) C07D 239/28 (2006.01) C07D 241/24 (2006.01) C07D 249/04 (2006.01) C07D 249/10 (2006.01) C07D 251/26 (2006.01) C07D 257/08 (2006.01) C07D 259/00 (2006.01) C07D 261/08 (2006.01) C07D 401/12 (2006.01) C07D 401/1

Patent

CA 2213584

The invention relates to an effective and efficient process for the preparation of azinyl acid chloride compounds of formula I, Image (I) (ring Az is defined in the specification). In this process a trichloromethylazine of formula II Az-CCI3 (II) is treated with an acid which is capable of forming an acid chloride that can be distilled off during the course of the reaction under reduced pressure in the presence of an acidic catalyst, and to the use of the compounds of formula I obtained according to this process for the preparation of (hetero)aryloxyazinylcarboxamides.

Méthode efficiente et efficace pour préparer des chlorures d'acide azinyliques de formule Image (I) (le cycle Az est défini dans la spécification). Dans ce procédé, une trichlorométhylazine de formule Az-CCI3 (II) est traitée avec un acide pouvant former un chlorure d'acide, distillable pendant le une réaction sous pression réduite en présence d'un catalyseur acide; l'invention porte aussi sur l'utilisation des composés de formule I obtenus selon ce procédé pour la préparation d'(hétéro)aryloxyazinyl-carboxamides.

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